FIG 2.

Summaries of the loci of multiple independent growth-enhancing reverting mutations obtained for the S1b mutant (A) and the S2b mutant (B). (C) Alignment of the amino acid sequences of the MHV and SARS-CoV N proteins. Domain boundaries and the mutations of all 18 individual S1b and S2b revertants are shown. The SARS-CoV N1b and N2b domains that are contained in the S1b and S2b mutants, respectively, are boxed. GenBank accession numbers for the sequences shown are AY700211 for MHV-A59 and AY278741 for SARS-CoV strain Urbani.