FIG 1 .

MeV-specific T-cell responses after nebulized (Neb) and intramuscular (IM) immunization with LAV. T-cell responses were assessed by IFN-γ ELISpot assays. PBMCs were stimulated with overlapping peptides from the hemagglutinin (H) (A) or fusion (F) (B) proteins. Numbers of MeV-specific spot-forming cells (SFCs) were determined by averaging spots in duplicate peptide-stimulated wells and subtracting spots in unstimulated wells. Data are presented as average numbers of SFCs/10⁶ PBMCs + the standard error of the mean (SEM) for each group (n = 3). No significant differences were detected (H-specific responses, 2 weeks, P = 0.13; 4 weeks, P = 0.35; Student’s t test).