Table 2. Values Used to Calculate the Intrinsic DSPC Bilayer/Water Partition Coefficients for TPT Species at pH 4 and 37 °Ca.
lipid
suspensions |
|||
---|---|---|---|
parameters | 0.48 mg/mL | 5.44 mg/mL | 15.3 mg/mL |
total TPT (μM) | 0.94 | 4.99 | 15.44 |
t1/2 (h) | 17 ± 2 | 19 ± 2 | 19 ± 3 |
K′ | 73 ± 2 | 46 ± 4 | 23 ± 3 |
f1 | 0.99 | 0.95 | 0.83 |
ΣiCi | 0.6 | 0.6 | 0.6 |
δ1 | 1.3 ± 0.1 | 1.8 | 2.3 |
δ2 | 1.6 ± 0.3 | 3.2 | 5.3 |
95% confidence intervals are shown where applicable.