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Synthetic collagen mimetic matrices. (A) Hierarchical self-assembly of the KOD peptide into a collagen triple helix with sticky ends indicating Lys-Asp salt bridges and unpaired Lys and Asp residues that allow for supramolecular assembly into fiber networks resembling native collagen, as noted by critical point dried samples under SEM (B), scale bar 1 μm. (C) Synthetic collagen matrices form a rigid gel that is resistant to mechanical handling by tweezers and other methods.
