Skip to main content
. Author manuscript; available in PMC: 2014 Jun 4.
Published in final edited form as: JAMA. 2013 Dec 4;310(21):2289–2296. doi: 10.1001/jama.2013.281954

Table 1.

Substances Used at Initial Episode, if Known, 1975–2009a

Substance No. (%)
Total (N = 242) Men (n = 231) Women (n = 11)
Opioids 151 (62) 145 (63) 6 (55)
 Intravenous 137 (57) 132 (57) 5 (45)
  Fentanyl 114 (47) 109 (47) 5 (45)
  Sufentanil 21 (9) 20 (9) 1 (9)
  Other intravenous opioid 39 (16) 38 (16) 1 (9)
 Oral 26 (11) 25 (11) 1 (9)
Alcohol 85 (35) 82 (35) 3 (27)
Anesthetics/hypnotics 46 (19) 43 (19) 3 (27)
 Propofol 11 (5) 9 (4) 2 (18)
 Ketamine 6 (2) 6 (3) 0
 Inhaled 6 (2) 6 (3) 0
 Benzodiazepines 30 (12) 28 (12) 2 (18)
Marijuana/cocaine 51 (21) 50 (22) 1 (9)
 Marijuana 33 (14) 32 (14) 1 (9)
 Cocaine 30 (12) 30 (13) 0
Othersb 33 (14) 29 (13) 4 (36)
a

The substance(s) used during the initial episode of abuse were known in 242 (63%) individuals, and unknown in 142 (37%) individuals. Eighty-five individuals (35%) used more than 1 substance (3 women [27%] and 82 men [35%]), so columns may not sum to total.

b

Others include diphenhydramine, 3,4-methylenedioxy-N-methamphetamine (MDMA), psilocybin mushrooms, lysergic acid diethylamide (LSD), methamphetamines, dexedrine, promethazine, and butalbital.