Table 2.
Schettgen et al. (2008) Aachen, Germany |
Eckert et al. (2011) Erlangen, Germany |
Alwis et al. (2012) Atlanta, GA, U.S.A. |
||||
---|---|---|---|---|---|---|
Accuracy, % (Range) |
Qhigh: 114 (104–129) |
Qlow: 70 (64–78) |
— (95–106) |
105 (101–109) |
||
Precision (CV, %) Intraday / Interday |
Qhigh: 7.3 / 13.4 |
Qlow: 4.9 / 22.2 |
< 10 / < 10 | — / (6.6–8.5) | ||
LOD, pmol/mL | 23 | 23 | 5.9 | |||
Smokers | Nonsmokers | Smokers | Nonsmokers | Smokers | Nonsmokers | |
Subjects, n | 14 | 14 | 40 | 54 | 347 | 1,203 |
Median 2-HPMA, pmol/mg creatinine (Range) |
170 (< 23–934) |
21 (< 23–333) |
209 (14–1235) |
55 (14–122) |
— | — |
Mean 2-HPMA, pmol/mL (± S.D.) |
— | — | — | — | 837 (± 1063) |
367 (± 534) |