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. 2014 Apr 21;9(4):e95364. doi: 10.1371/journal.pone.0095364

Table 3. Relationship between the primary or occult primary and node metastasis regarding HPV physical status.

HPV16 Physical Status in Node Metastasis
HPV16 Physical Status in Primary Integrated (%) Mixed (%) Episomal (%) P Value*
Oropharynx (N = 18) Integrated 10 (56) 0 (0) 0 (0) <0.0001
Mixed 0 (0) 8 (44) 0 (0)
Episomal 0 (0) 0 (0) 0 (0)
Occult tonsil (N = 3) Integrated 1 (33) 0 (0) 0 (0) <0.0001
Mixed 0 (0) 2 (67) 0 (0)
Episomal 0 (0) 0 (0) 0 (0)

*Symmetry of HPV physical status between the primary tumor and its corresponding node metastasis in oropharyngeal cancer and occult tonsil cancer patients was examined using the kappa test.

HPV: human papillomavirus.