Table 3. Relationship between the primary or occult primary and node metastasis regarding HPV physical status.
HPV16 Physical Status in Node Metastasis | |||||||||
HPV16 Physical Status in Primary | Integrated | (%) | Mixed | (%) | Episomal | (%) | P Value* | ||
Oropharynx | (N = 18) | Integrated | 10 | (56) | 0 | (0) | 0 | (0) | <0.0001 |
Mixed | 0 | (0) | 8 | (44) | 0 | (0) | |||
Episomal | 0 | (0) | 0 | (0) | 0 | (0) | |||
Occult tonsil | (N = 3) | Integrated | 1 | (33) | 0 | (0) | 0 | (0) | <0.0001 |
Mixed | 0 | (0) | 2 | (67) | 0 | (0) | |||
Episomal | 0 | (0) | 0 | (0) | 0 | (0) |
*Symmetry of HPV physical status between the primary tumor and its corresponding node metastasis in oropharyngeal cancer and occult tonsil cancer patients was examined using the kappa test.
HPV: human papillomavirus.