Table 3. Univariable and multivariable analyses on LMP10 staining of TSCC and BOTSCC in relation to DFS and OS.

		DFS						OS
		Univariable			Multivariable§			Univariable			Multivariable§
		HR	95% CI	p-value	HR	95.0% CI	p-value	HR	95.0% CI	p-value	HR	95.0% CI	p-value
HPV-positive
Nucleus	Fraction*	3.254	1.349–7.850	.009	2.755	1.121–6.767	.027	1.673	0.813–3.445	.162	1.340	0.640–2.805	.438
	Intensity**	2.729	1.019–7.310	.046	2.253	0.827–6.135	.112	2.228	0.956–5.194	.063	1.792	0.754–4.261	.187
Cytoplasm	Fraction	2.070	0.886–4.838	.093	1.869	0.797–4.382	.150	.590	0.281–1.240	.164	.521	0.247–1.098	.086
	Intensity	1.494	0.620–3.604	.371	1.346	0.557–3.254	.509	.703	0.343–1.441	.336	.617	0.300–1.269	.189
HPV-negative
Nucleus	Fraction	1.238	0.436–3.518	.688	1.274	0.447–3.631	.650	.815	0.408–1.627	.562	.958	0.474–1.935	.905
	Intensity	1.573	0.452–5.481	.477	1.645	0.461–5.871	.443	1.092	0.474–2.519	.836	1.194	0.516–2.764	.679
Cytoplasm	Fraction	.143	0.033–0.631	.010	.154	0.035–0.684	.014	.234	0.090–0.610	.003	.281	0.107–0.739	.010
	Intensity	.204	0.071–0.584	.003	.219	0.073–0.653	.006	.405	0.201–0.818	.012	.487	0.236–1.004	.051

^§Adjusted for age and tumor stage,

*absent/low vs moderate/high,

**absent vs weak/moderate/high.

Abbreviations: HR, Hazard Ratio; CI, Confidense Interval.