Table 4. Multivariable analysis of LMP10 and HLA class I expression on TSCC/BOTSCC in relation to DFS.
DFS | |||||||
HPV-positive | HPV-negative | ||||||
Variables | HR | 95% CI | p-value | Variables | HR | 95% CI | p-value |
LMP10 fraction nucleus* | 2.817 | 1.145–6.928 | .024 | LMP10 fraction cytoplasm* | .124 | 0.027–0.565 | .007 |
HCA2 intensity** | 3.326 | 1.369–8.076 | .008 | HCA2 fraction* | .267 | 0.092–0.775 | .015 |
Age | 1.035 | 0.993–1.079 | .105 | Age | .995 | 0.940–1.054 | .870 |
Stage I-IIIvsIV | 1.017 | 0.442–2.340 | .969 | Stage I-IIIvsIV | 1.184 | 0.447–3.136 | .734 |
*absent/low vs moderate/high,
**absent/weak vs strong.
Abbreviations: HR, Hazard Ration; CI, Confidence Interval.