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. 2014 Apr 21;9(4):e95694. doi: 10.1371/journal.pone.0095694

Figure 7. SH-11052 inhibits VEGF mediated Akt signaling.

Figure 7

Phosphorylation of VEGFR2 (A) and Akt (C) was monitored in HRECs upon VEGF stimulation in the presence of varying concentrations of 2. (B & D) Densitometry was performed using Quantity One software and analyzed using GraphPad Prism. The lines indicate the mean ± SEM of three biological replicates, * indicates p<0.05 and ** indicates p<0.01 compared to VEGF treatment alone (ANOVA with Dunnett's post hoc test).