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. 2014 Apr 21;9(4):e95633. doi: 10.1371/journal.pone.0095633

Table 2. Types of KoRV polymorphisms detected across 6 museum specimens of koalas.

LTRs gag leader gag pol env Total
Sequence length 505 bp 465 bp 1566 bp 3384 bp 1980
Shared Private Shared Private Shared Private Shared Private Shared Private Shared Private
Indels 0 0 2 0 0 0 0 0 0 0 2 0
Polymorphisms of which: 17 14 9 4 17 12 19 19 12 13 74 64
Non-coding 17 14 9 4 NA NA NA NA NA NA 26 18
Coding region of which NA NA NA NA 17 12 19 19 12 13 48 44
Stop codon NA NA NA NA 0 0 0 1 1 1 1 2
Synonymous NA NA NA NA 8 5 9 7 3 3 20 15
Non-synonymous of which: NA NA NA NA 9 7 10 11 8 9 27 27
Not radical NA NA NA NA 7 3 5 8 2 3 14 14
Radical NA NA NA NA 2 4 5 3 6 6 13 13

LTRs are the long terminal repeats, sequence length is from the KoRV reference sequence AF151794. Private polymorphisms were those detected in one koala, shared polymorphisms in more than one koala; NA is not applicable. Radical changes are atypical amino acid substitutions with negative scores in both BLOSUM62 and BLOSUM90 matrices. Radical mutations in env (boldface) were more common (pā€Š=ā€Š0.040) than in gag-pol, relative to other amino acid changes.