Table 5. Twenty-eight day mortality risk of patients with severe pneumonia.

Variable	No. of deaths/no. of episodes (%)	p	Adjusted Odds Ratio (95% CI)	p
All cases	94/262 (35.9)
Sex
Male	68/191(36.6)	0.879
Female	26/71 (35.6)
Shock at the time of admission		0.001	1.99 (1.15–3.46)	0.014
No	37/139 (26.6)
Yes	57/123 (46.3)
Structural lung disease		0.640
No	74/202 (36.6)
Yes	20/60 (37.1)
COPD		0.396
No	86/234 (36.8)
Yes	8/28 (28.6)
Interstitial lung disease		0.121	1.93 (0.70–5.34)	0.206
No	84/243 (33.3)
Yes	10/19 (27.6)
Diabetes mellitus		0.077	0.72 (0.39–1.35)	0.305
No	73/186 (38.6)
Yes	21/76 (27.6)
Solid cancer		0.330
No	76/203 (37.4)
Yes	18/59 (30.5)
Hematologic malignancy		0.014	1.06 (0.53–2.11)	0.870
No	58/186 (33.3)
Yes	36/76 (47.4)
Immunocompromised state		<0.001	2.63 (1.51–4.60)	<0.001
No	34/143 (36.2)
Yes	60/119 (63.8)
McCabe and Jackson criteria		0.002	1.73 (0.93–3.21)	0.084
Nonfatal	23/97 (23.3)
Rapidly fatal or ultimately fatal	71/165 (42.4)
Pathogen identified		0.520
No	24/61 (37.7)
Yes	70/201 (34.8)
Pathogen		0.321
Bacteria only	40/130 (30.8)
Virus(es) only	12/31 (38.7)
Bacteria/virus coinfection	4/21 (19.0)
S. aureus		0.593
No	77/210 (36.7)
Yes	17/52 (32.7)
P. aeruginosa		0.077	0.47 (0.17–1.26)	0.131
No	88/233 (37.8)
Yes	6/29 (20.7)
Rhinovirus		0.198	0.38 (0.10–1.48)	0.119
No	91/247 (36.8)
Yes	3/15 (20.0)
Parainfluenza virus		0.500
No	87/246 (35.4)
Yes	7/16 (43.8)
Influenza virus		0.501
No	89/251 (35.5)
Yes	5/11 (45.5)
Respiratory syncytial virus		0.889
No	88/246 (35.8)
Yes	6/16 (37.5)
Cytomegalovirus		0.472
No	91/256 (35.5)
Yes	3/6 (50.0)
Human coronavirus		0.142	9.67 (0.85–109.49)	0.067
No	91/258 (35.3)
Yes	3/4 (75.0)

COPD = chronic obstructive pulmonary disease.