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Mice were pretreated with CP 55940 (CP, 0.3 mg/kg) or vehicle 30 minutes prior to pilocarpine (325 mg/kg). Seizure severity scores and the proportion of mice having at least one clonic-tonic seizure were compared between CP-treated (n = 8) and vehicle-treated mice (n = 8). Data are presented as medians ± upper and lower quartiles.
