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. 2014 Apr 21;9(4):e95730. doi: 10.1371/journal.pone.0095730

Figure 7. Difference of ENaC-dependent trans-epithelial current in Reissner’s membrane (A) and the extramacular roof epithelium of the saccule (B) at P0, P6, and P56.

Figure 7

The ENaC-dependent current in Reissner’s membrane of Pds+/+ and Pds−/− mice was significantly increased according to the development The current was not changed in saccular extramacular membrane of Pds+/+ mice according to the development, but it was significantly increased at P56 of Pds−/− mice. The current difference between Pds+/+ and Pds−/− mice was significant at P56 both in Reissner’s membreane and saccular extramacular membrane. [p<0.05 (One Way ANOVA with Holm-Sidak post-test) at P6 and P56 of Pds+/+ mice and p<0.05 (One Way ANOVA with Dunn’s post-test) at P56 of Pds−/− mice]. *p<0.05 in the current difference among P0, P6, and P56 groups for each genotype (One Way ANOVA with Holm-Sidak/Dunn’s post-test), **P<0.05 in the current density differences between Pds+/+ and Pds−/− mice at P0, P6, and P56 (Mann-Whitney Rank Sum test), numbers above the bars represent the number of trans-epithelial current measurements.