Figure 5. TPM enhanced functionality of PCat-siSurvivin in animal tumors on molecular and cellular levels.
Immunodeficient mice were implanted with tumors and treated as described in the Figure 4 legend. Tumors were excised and processed for immunohistochemical staining and quantitative image analysis of survivin, Ki67, and caspase-3. *p<0.05 between TPM and TPM+PCat-siSurvivin combination.