Figure 6. Number of activated microglial cells.

Number of activated microglial cells when C21 given either pre-stroke (A) or post-stroke. For pre-treatment, the effect of vehicle (saline; n = 6) and AT₂R agonist C21 (50 ng/kg/min; n = 5) on the number of activated microglia at 3 days after stroke. For post-stroke treatment, the effect of vehicle (saline; n = 7) and AT₂R agonist C21 (144 µg/kg/dose; n = 7) on the number of activated microglia at 3 days after stroke. Data expressed as number of activated microglia per 0.5 mm² area in non-infarcted (filled columns) and infarcted (open columns) region on the ipsilateral hemisphere. Mean data±SEM. **P<0.01 vs. corresponding region in vehicle-control (2-tailed unpaired t test).