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Exposure (mean value) of paclitaxel in plasma, tumor, liver, and spleen following intravenous administration
|
Tissue AUC0-8(μM × h) |
Formulation |
|
|---|---|---|
| Cremophor EL:ethanol | Nanosuspension | |
| Plasma |
74.7 |
2.1 |
| Tumor |
52.1 |
17.5 |
| Liver |
269.1 |
1,701.1 |
| Spleen | 85.2 | 147.5 |
