Table 1.
Sequences and ESI-MS data of bcl-2 (1–6) and CXCR4 (7 and 8) targeted siRNA oligonucleotides
| Oligonucleotide sequence | Strand | Modification | Mass calcd | Mass found | |
|---|---|---|---|---|---|
| 1 | UCA-GGU-ACU-CAG-UCA-UCC-ACA-dTdT | AS | — | 7224.14 | 7224.03 |
| 2 | UGU-GGA-UGA-CUG-AGU-ACC-UGA-dTdT | S | — | 7361.22 | 7362.16 |
| 3 | UCA-GGU-ACU-CAG-UCA-UCC-ACA-dTdT | AS | 3′-Amino | 7403.21 | 7403.26 |
| 4 | UGU-GGA-UGA-CUG-AGU-ACC-UGA-dTdT | S | 3′-Amino | 7540.29 | 7540.15 |
| 5 | UCA-GGU-ACU-CAG-UCA-UCC-ACA-dTdT | AS | 3′-PEG | 7974.54 | 7974.14 |
| 6 | UGU-GGA-UGA-CUG-AGU-ACC-UGA-dTdT | S | 3′-PEG | 8111.62 | 8110.93 |
| 7 | AAA-CUC-ACA-CCC-UUG-CUU-GdTdT | AS | — | ||
| 8 | CAA-GCA-AGG-GUG-UGA-GUU-UdTdT | S | — | ||
| 9 | AAA-CUC-ACA-CCC-UUG-CUU-GdTdT | AS | 3′-PEG | ||
| 10 | CAA-GCA-AGG-GUG-UGA-GUU-UdTdT | S | 3′-PEG |