Fig. 2.

Inhibition of 5-HT-evoked current by ginger dry extract (Ginger ext.) and ondansetron (Ondan). (A) Serotonin (3 µM) was repeatedly applied with 4 min intervals with or without 5-HT₃ receptor antagonist ondansetron (10 nM). (B) CPBG-evoked current was blocked by 10 nM ondansetron. (C) The traces show that 5-HT-evoked currents were suppressed by 0.2 and 2 mg/ml ginger dry extract. Ginger extract was pre-applied 2 min before co-application with 3 µM 5-HT. The diagram shows summary of average 5-HT current change by 0.2 and 2 mg/ml ginger extract and 10 nM ondansetron treatments. ^*Significant difference from control (p≤0.01). Each column and vertical lines represent the mean±SEM.