Figure 1.
Illustration of domain combination similarity. The figure gives an example of the domain combination similarity of protein PA and PB, in which different shapes are drawn to represent different types of domains. The domain combination similarity of the two proteins is consisted of two parts: the context similarity, which is presented in the figure as the light grey part plus the dark black part, and the composition similarity, which is presented in the figure as the dark black. Domain composition of protein PA, denoted by DT(PA), is a set of domain types in protein PA. Domain context of PA, denoted by DC(PA), is a set of distinct domain types in the neighbor proteins of PA (PA included).