Table 1. Effects of aqueous extracts of V. doniana on liver function parameters in liver of CCl4 induced liver damage rats.
Group ( n=6) | ALT (U/I) | AST(U/I) | ALP(U/I) | Total protein (g/L) | Albumin (g/L) |
Normal control | 14.50±2.5abc | 43.33±29.8a | 89.70±25.3a | 66.28±3.4ab | 37.24±3.0b |
Vehicle control | 8.67±3.1a | 47.00±15.3a | 77.28±14.0a | 72.12±12.2ab | 35.59±4.0b |
CCl4 induced liver damage control | 26.00±2.0d | 70.00±5.0b | 147.20±15.9b | 58.48±3.4a | 26.58±1.4a |
CCl4+RE | 17.00±2.6bc | 46.67±11.5a | 87.17±9.1a | 62.38±3.4 a | 33.46±3.0b |
CCl4+SE | 9.50±4.1a | 46.67±10.4a | 95.68±33.6a | 79.92±6.7b | 33.96±0.9b |
CCl4+LE | 20.00±7.3cd | 47.50±14.4a | 96.60±31.4a | 70.18±5.9ab | 33.96±0.9b |
CCl4+Std | 12.50±13.8ab | 45.00±9.3a | 107.30±4.8a | 79.92±9.0b | 37.73±2.9b |
Values are means±SD. Values with different superscript down the colomn are significantly different (P<0.05).
CCl4+RE: CCl4 Induced liver damage rats+100 mg/kg body weight of aqueous root bark extract, CCl4+SE: CCl4 Induced liver damage rats+100 mg/kg body weight of aqueous stem bark extract, CCl4 + LE: CCl4 induced liver damage rats+100 mg/kg body weight of aqueous leaves extract, CCl4+Std: CCl4 induced liver damage rats+100 mg/kg body weight of Vitamin E.