Table 2.

Gene expression of cathepsin K, CD3, CD14 and of cytokines in tissue of patients with metallosis

Parameter	Cup	Muscle	Difference between groups calculated by Mann–Whitney test
Cathepsin K	2603.0 ± 1220.8*	968.4 ± 392.4	n.d.
CD3	288.6 ± 262.2	42.2 ± 26.4	p = 0.036
CD14	1806.2 ± 1211.9	334.2 ± 247.7	p = 0.012
CXCL8	677.0 ± 355.5	27.0 ± 20.8	p = 0.043
IL1ß	101.4 ± 90.7	9.0 ± 3.5	p = 0.043
CXCL2	276.5 ± 125.0	92.8 ± 51.5	p = 0.040
MRP14	82376.8 ± 78340.0	377.4 ± 396.0	p = 0.040
RANK	10.9 ± 9.8	8.2 ± 5.7	n.d.
RANKL	4.1 ± 4.0	0.2 ± 0.2	n.d.
TNFα	11.5 ± 4.0	7.3 ± 1.0	n.d.
CXCL10	184.7 ± 239.5	131.6 ± 147.8	n.d.
CCL2	1612.1 ± 1958.9	652.0 ± 144.8	n.d.

*copy number; n.d. = not different.