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mRNA expression levels were determined by real-time PCR. Increased expression of BCL-6, CXCR5, IL-6R, IL-4, and IL-21 mRNA in CXCR5+CD4+ T cells in patients with chronic HBV infection (n = 16) compared to healthy controls (n = 16). Data are presented as the mean ± SD. *,p < 0.05; **, p < 0.01.
