TABLE 2 .
Genes and promoters with SNP densities significantly higher than the chromosomal average
| Locus tag(s) | Gene(s) | Density (SNPs/bp) | P value | Product | Categorya | Localization(s)b | Bvgc |
|---|---|---|---|---|---|---|---|
| 3783BP | ptxA | 0.01111 | 3.3E-03 | Pertussis toxin subunit A precursor | Vir | E | + |
| 2416BP | cysB | 0.01053 | 2.9E-03 | LysR family transcriptional regulator | Reg | C | |
| BP3783P | ptxP | 0.07143 | 4.7E-18 | Pertussis toxin promoter | Vir | E | + |
| BP2936P | 0.03623 | 2.0E-02 | Putative methylase promoter | Exp | CM | + | |
| BP1878P, BP1879P |
bvgP, fhaBP |
0.02582 | 3.4E-05 | Virulence factor transcription regulator promoter, filamentous hemagglutinin | Vir | C, OM | +, + |
| BP3723P, BP3724P |
0.02047 | 1.8E-02 | Hypothetical protein promoter | Hyp | U, C |
a
Functional category: Vir, virulence-associated genes; Reg, regulation; Exp, exported proteins; Hyp, hypothetical proteins.
b
Subcellular localization: E, extracellular; C, cytoplasmic; CM, cytoplasmic membrane; OM, outer membrane; U, unknown.
c
Regulation by Bvg: +, activated; blank cells, not activated or repressed.