Standard dosage	60 mg/m2 daily on days 8–21.
Contraindications	Hypersensitivity to drug or components, myelosuppression.
Main drug interactions	Disulfiram-like interaction with alcohol. Tricyclic antidepressants and sympathomimetics may induce hypertensive crisis. Rare cases of encephalopathy.
Main side effects	Encephalopathy, nausea, vomiting, myelosuppression, photosensitivity.
Special points	Weak monoamine oxidase inhibitor requiring patients to avoid foods that are tyramine-rich. Best taken on an empty stomach at bedtime. Dosed in 50-mg tablets; a patient’s individual dose should be rounded to the nearest 50 mg based on dry weight.
Cost	$24 per pill, roughly $1000 per cycle.