Table 1.
Comparison of mathematically optimized methods for equilibration of human oocytes with 6 mol/L EG
| Procedure | Concentration parameterization | Goal cell volume | Goal EG Conc. ( s f / w f ) | Toxicity ( J α ) |
|---|---|---|---|---|
| Addition |
Piecewise linear |
Isotonic |
30 |
396 |
| Addition |
Piecewise linear |
Not specified |
30 |
32.3 |
| Addition |
2-step piecewise constant |
Not specified |
30 |
49.5 |
| Addition |
3-step piecewise constant |
Not specified |
30 |
42.7 |
| Removal |
Piecewise linear |
Isotonic |
0 |
38.4 |
| Removal |
Piecewise linear |
Not specified |
0 |
12.1 |
| Removal |
2-step piecewise constant |
Not specified |
0 |
12.8 |
| Removal | 3-step piecewise constant | Not specified | 0 | 12.4 |