Table 1.
Clinical and surgical characteristics of patients
| Variables |
Extended thymectomy |
Limited thymectomy |
P value |
|---|---|---|---|
| (n = 239) | (n = 103) | ||
| Age, mean ± SD |
45.4 ± 12.10 |
49.7 ± 13.69 |
0.005 |
| Sex |
|
|
0.196 |
| Male |
123 (51.5) |
61 (59.2) |
|
| Female |
116 (48.5) |
42 (40.8) |
|
| MG |
|
|
< 0.0001 |
| No |
53 (22.2) |
92 (89.3) |
|
| Yes |
186 (77.8) |
11 (10.7)a |
|
| WHO histologic type |
|
|
< 0.0001 |
| A |
8 (3.3) |
15 (14.6) |
|
| AB |
36 (15.1) |
42 (40.8) |
|
| B1 |
44 (18.4) |
14 (13.6) |
|
| B2 |
59 (24.7) |
19 (18.4) |
|
| B3 |
92 (38.5) |
13 (12.6) |
|
| Operative approach |
|
|
< 0.0001 |
| Median sternotomy |
167 (69.9) |
11 (10.7) |
|
| Thoracotomy |
13 (5.4) |
32 (31.1) |
|
| VATS |
55 (23.0) |
55 (53.4) |
|
| Clamshell |
4 (1.7) |
- |
|
| Cervicotomy |
- |
2 (1.9) |
|
| Robotic |
- |
3 (2.9) |
|
| Tumor size, mean ± SD |
5.7 ± 3.13 |
6.9 ± 2.95 |
0.001 |
| Masaoka –Koga stage |
|
|
0.005 |
| I |
110 (46.0) |
66 (64.1) |
|
| IIa |
50 (20.9) |
21 (20.4) |
|
| IIb |
33 (13.8) |
12 (11.7) |
|
| III |
34 (14.2) |
4 (3.9) |
|
| IVa |
10 (4.2) |
- |
|
| IVb |
2 (0.8) |
- |
|
| Adjuvant therapy |
|
|
< 0.0001 |
| None |
113 (47.3) |
79 (76.7) |
|
| Radiotherapy |
96 (40.2) |
22 (21.4) |
|
| Chemotherary |
6 (2.5) |
0 (0.0) |
|
| Chemoradiation |
24 (10.0) |
2 (1.9) |
|
| Follow-up time, mean ± SD | 79.6 ± 59.49 | 81.2 ± 65.23 | 0.830 |
apost-thymectomy myasthenia gravis.