Table 2.
Clinical and surgical characteristics of patients after 1:1 exact matching by size and stage of tumor
| Variables |
Extended thymectomy |
Limited thymectomy |
P value |
|---|---|---|---|
| (n = 86) | (n = 86) | ||
| Age, mean ± SD |
45.3 ± 12.14 |
49.7 ± 13.60 |
0.027 |
| Sex |
|
|
0.284 |
| Male |
43 (50.0) |
51 (59.3) |
|
| Female |
43 (50.0 |
35 (40.7) |
|
| MG |
|
|
< 0.0001 |
| No |
22 (25.6) |
76 (88.4) |
|
| Yes |
64 (74.4) |
10 (11.6)a |
|
| WHO histologic type |
|
|
0.001 |
| A |
6 (7.0) |
12 (14.0) |
|
| AB |
15 (17.4) |
34 (39.5) |
|
| B1 |
20 (23.3) |
12 (14.0) |
|
| B2 |
17 (19.8) |
17 (19.8) |
|
| B3 |
28 (32.6) |
11 (12.8) |
|
| Operative approach |
|
|
< 0.0001 |
| Median sternotomy |
61 (70.9) |
8 (9.3) |
|
| Thoracotomy |
8 (9.3) |
27 (31.4) |
|
| VATS |
16 (18.6) |
47 (54.7) |
|
| Clamshell |
1 (1.2) |
- |
|
| Cervicotomy |
- |
2 (2.3) |
|
| Robotic |
- |
2 (2.3) |
|
| Tumor size, mean ± SD |
6.4 ± 2.67 |
6.4 ± 2.67 |
0.943 |
| Masaoka –Koga stage |
|
|
>0.999 |
| I |
51 (59.3) |
51 (59.3) |
|
| IIa + IIb |
31 (36.1) |
31 (36.1) |
|
| III |
4 (4.6) |
4 (4.6) |
|
| IVa + IVb |
- |
- |
|
| Adjuvant therapy |
|
|
0.069 |
| None |
50 (58.1) |
64 (74.4) |
|
| Radiotherapy |
30 (34.9) |
21 (24.4) |
|
| Chemotherary |
2 (2.3) |
0 (0.0) |
|
| Chemoradiation |
4 (4.7) |
1 (1.2) |
|
| Follow-up time, mean ± SD |
94.5 ± 65.35 |
85.6 ± 67.92 |
0.386 |
|
Pattern of recurrence |
|
|
|
| Local |
0 |
1 |
|
| Local + regional |
0 |
2 |
|
| Regional |
3 |
7 |
|
| Distant | 2 | 0 |
apost-thymectomy myasthenia gravis.