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Thy1-aSyn mice did not show alterations in the PER2 rhythm within the SCN. Mice were held in DD and wheel running activity was measured to determine circadian phase. IHC was used to measure PER2 immunoreactivity in the SCN of Thy1-aSyn and WT controls. Tissue was collected in the subjective day or subjective night. Photomicrographs of SCN tissue of each genotype in low (10X) and higher (40X) magnification at 3 mo of age. Data from Kudo et al., 2011b.
