Table 2.
PROTEIN | EXTRACELLULAR FUNCTION | INTRACELLULAR FUNCTION |
---|---|---|
IL-1α | Pro-inflammatory cytokine | Activator of transcription |
IL-1β | Pro-inflammatory cytokine | - |
IL-18 | Pro-inflammatory cytokine | - |
Caspase I (ICE) | ? | IL-1/IL-18 converting enzyme |
HMGB1 | Pro-inflammatory cytokine | Chromatin component |
IL-16 | Pro-inflammatory cytokine | - |
MIF | Pro-inflammatory cytokine | Transcription factor modulator |