Figure 2.

STBM produced from normal and preeclamptic placentas induce a similar dose-dependent pro-inflammatory response in monocytes. Primary monocytes were incubated with increasing concentrations of STBM prepared from normal (STBM-NP) or preeclamptic (STBM-PE) placentas for 16 h. The cellular secretion of IL-8 (A) and IL-6 (B) was measured by conventional ELISA. Results are illustrated as mean ± SEM of two independent monocyte co-culture experiments with five STBM-NP preparations and three STBM-PE preparations. There is no statistical difference between the responses generated by the two different STBM populations.