Skip to main content
. Author manuscript; available in PMC: 2014 Apr 22.
Published in final edited form as: Genet Epidemiol. 2013 Nov 18;38(1):84–93. doi: 10.1002/gepi.21771

Table 2.

Significantly associated SNPs with P < 7 × 10−7 in the analysis of multiplicative interaction between 71,527 SNPs and 10 environmental risk factors for breast cancer, using the 2df test

SNP Chromosome Region Position build 36 Environmental variable P-value marginal OR marginal P-value interaction OR interaction P-value 2df test
rs12197388 6 ARID1B 161630341 Parity 5.69 × 10−8 1.09 0.37 1.01 2.68 x 10−7
Menarche 5.24 × 10−8 1.09 0.52 0.99 2.99 × 10−7
rs10483028a 21 21q22.12 35595443 BMI post 1.70 × 10−5 1.17 3.19 × 10−5 0.84 1.68 × 10−8
rs2242714a 21 21q22.12 35599557 BMI post 2.47 × 10−5 1.16 4.12 × 10−5 0.84 3.07 × 10−8
a

These two SNPs were also identified to show statistically significant multiplicative interaction with BMI using the H2, Cocktail, and EDG × E approaches (see Supplementary Tables S4a–c).