Table 2.
Prevalence of CV Risk Factors in CCM1-CHM Subjects
| Children < 18 y of Age | Adults ≥ 18 y of Age | |||
|---|---|---|---|---|
|
| ||||
| CV Risk Factors | N | Prevalence (%) | N | Prevalence (%) |
| Gender (female) | 23 | 54.8 | 95 | 66.4 |
| Obesity | 9 | 21.4 | 58 | 40.6 |
| Diabetes | 0 | 0.0 | 19 | 13.3 |
| Hypertension | 0 | 0.0 | 35 | 24.5 |
| Hyperlipidemia | 0 | 0.0 | 39 | 27.3 |
| Smoking status | 2 | 4.8 | 57 | 39.9 |
|
| ||||
| Related Quantitative Traits | Mean ± SD | Range | Mean ± SD | Range |
|
| ||||
| Age at enrollment (years) | 11.4 ± 3.3 | 6.6 – 17.5 | 46.1 ± 15.1 | 18.0 – 84.9 |
| Z-score BMI or BMI (kg/m2) | 0.4 ± 1.4 | −2.7 – 2.8 | 29.1 ± 6.8 | 17.0 – 50.9 |
| HbA1C (%) | 5.5 ± 0.3 | 5.0 – 6.0 | 5.9 ± 1.0 | 4.8 – 14.3 |
| SBP (mmHg) | 108.3 ± 11.4 | 74 – 128 | 126.2 ± 16.8 | 86.0 – 168.0 |
| DBP (mmHg) | 64.2 ± 9.2 | 43.0 – 83.0 | 77.9 ± 12.0 | 50.0 – 110.0 |
| Total Chol (mg/dL) | 157.2 ± 30.8 | 106.0 – 236.0 | 187.4 ± 40.0 | 113.0 – 296.0 |
| HDL (mg/dL) | 52.7 ± 13.5 | 22.0 – 80.0 | 52.4 ± 18.4 | 22.0 – 130.0 |
| LDL (mg/dL) | 85.9 ± 27.9 | 31.0 – 155.0 | 105.0 ± 32.3 | 37.0 – 215.0 |
| Triglycerides (mg/dL) | 92.6 ± 46.4 | 43.0 – 269.0 | 150.0 ± 87.9 | 42.0 – 543.0 |
| Pack-years of cigarette smoking | 1.0 ± 0.0 | - | 9.7 ± 14.2 | 1.0 – 74.0 |