Table 3.
CV Risk Factors Associated with Lesion Count in CCM1-CHM Subjects at Study Enrollment. Table gives proportional increase (PI) (or decrease if less than 1) in lesion count associated with each risk factor, along with 95% confidence intervals and P-values.
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| * Model 1 | ** Multivariable Model | |||
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| CV Risk Factors | PI (95%CI) | P-value | PI (95%CI) | P-value |
| Age at enrollment | - | - | 1.05 (1.04–1.06) | < 0.001 |
| Male Gender | 1.42 (1.02–1.98) | 0.035 | 1.41 (1.01–1.96) | 0.042 |
| Obesity | 0.57 (0.41–0.78) | 0.001 | 0.57 (0.42–0.78) | 0.001 |
| Diabetes | 0.91 (0.47–1.79) | 0.794 | - | - |
| Hypertension | 0.72 (0.47–1.11) | 0.137 | - | - |
| Hyperlipidemia | 0.99 (0.70–1.43) | 0.992 | - | - |
| Smoking status | 0.93 (0.64–1.34) | 0.696 | - | - |
*
Each risk factor was adjusted for age at enrollment
**
Included all risk factors significantly associated with lesion count in Model 1