Table 4.
CV Quantitative Traits Associated with Lesion Count in CCM1-CHM Adults (≥18 years of age) at Study Enrollment. Table gives proportional increase (PI) (or decrease if less than 1) in lesion count associated with each quantitative trait, along with 95% confidence intervals and P-values.
|
|
||||
|---|---|---|---|---|
| * Model 1 | ** Multivariable Model | |||
|
| ||||
| Quantitative Traits | PI (95%CI) | P-value | PI (95%CI) | P-value |
| Age (5 units - years) | - | - | 1.38 (1.32 – 1.46) | <0.001 |
| BMI (5 units - kg/m2) | 0.83 (0.74 – 0.93) | 0.002 | 0.87 (0.76 – 0.99) | 0.035 |
| HbA1C (10 units - %) | 0.96 (0.17 – 5.22) | 0.960 | - | - |
| SBP (10 units - mmHg) | 0.84 (0.76 – 0.93) | 0.002 | 0.87 (0.79 – 0.97) | 0.011 |
| DBP (10 units - mmHg) | 0.88 (0.75 – 1.02) | 0.098 | - | - |
| Total Chol (10 units - mg/dL) | 1.01 (0.97 – 1.06) | 0.559 | - | - |
| HDL (10 units - mg/dL) | 1.06 (0.93 – 1.21) | 0.387 | - | - |
| LDL (10 units - mg/dL) | 1.03 (0.97 – 1.09) | 0.355 | - | - |
| Triglycerides (10 units - mg/dL) | 0.98 (0.96 – 1.01) | 0.167 | - | - |
| Pack-years of cigarette smoking (10 units) | 1.07 (0.94 – 1.21) | 0.311 | - | - |
*
Each quantitative trait was adjusted for age at enrollment and gender
**
Included all quantitative traits significantly associated with lesion count in Model 1