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. Author manuscript; available in PMC: 2015 Apr 1.
Published in final edited form as: Am J Ophthalmol. 2014 Jan 2;157(4):799–806. doi: 10.1016/j.ajo.2013.12.023

Table 3.

Odds ratios and 95% confidence intervals for dry eye symptoms by risk factor stratified by age, the Beaver Dam Offspring Study 2005–2008 a,b

Risk factor < 50 years of age ≥50 years of age Overall
Agec (per increase in age group) 1.08 (0.85, 1.37) 1.31 (1.03, 1.65) 1.12 (1.00, 1.27)
Sex
 Male 1.00 (ref) 1.00 (ref) 1.00 (ref)
 Female 1.41 (1.02, 1.95) 1.76 (1.25, 2.47) 1.45 (1.14, 1.85)
Contact Lens Use
 Past 0.92 (0.61, 1.38) 1.09 (0.83, 1.43)
 Current 2.38 (1.67, 3.37) 2.09 (1.56, 2.79)
Chronic Conditions
 Arthritis 2.14 (1.46, 3.13) 1.41 (1.09, 1.82)
 Allergies 1.49 (1.05, 2.10) 2.06 (1.37, 3.10) 1.54 (1.18, 2.01)
 Thyroid Disease 1.40 (1.00, 1.97)
 Migraine Headache 1.71 (1.10, 2.65) 1.44 (1.10, 1.90)
Medication Use
 Antihistamines 1.80 (1.23, 2.63) 1.41 (1.07, 1.86)
 Steroids 1.47 (1.10, 1.97)
 Benzodiazepine 2.08 (1.21, 3.56)
 Multivitamin Use 1.44 (1.06, 1.94)
a

Listed as OR (95% CI)

b

Multivariable final models generated by stepwise regression. The model for each category includes the risk factors with a listed estimate.

c

Age groups (years): 21–34, 35–44, 45–54, 55–64, 65–84