Table 1.
Disease characteristics of CAH cases.
| Male N = 20 | Female N = 29 | |
|---|---|---|
| Age (in months) at starting treatmenta | 1.0 (1.5) | 0.5 (0.6) |
| Age in years at study entry | 11.6 (4.3)a | 11.9 (3.4)a |
| 11.5 (6–18)b | 12.0 (6–17)b | |
| Presentation at diagnosis | ||
| Salt wasting featuresc | 17 (85) | 23 (79) |
| No salt wasting featuresc | 3 (15) | 6 (21) |
| Ambiguous genitaliac | 0 | 29 (100) |
| Hypertensionc | 0 | 0 |
| Height SDS at the time of CBCLa | −1.1 (1.6) | −1.4 (2.2) |
| Serum 17-OHP in nmol/L at the time of CBCLa | 46.0 (182.1) | 8 (131.1) |
| Glucocorticoid dose in mg/m2/day near the time of CBCLa | 17.3 (4.9) (CI: 15–19.6) |
14.4 (2.4) (CI: 13.9–15.7) |
| Prader ratingc | ||
| 1 | 4 (14) | |
| 2 | 8 (28) | |
| 3 | 14 (48) | |
| 4 | 3 (10) | |
| Genitoplastyc | ||
| Nil | 4 (14) | |
| Clitoroplasty | 11 (38) | |
| Clitoroplasty and vaginoplasty | 14 (48) | |
| Age in years at the first genitoplastya | 2.3 (2.7) | |
| Serum testosterone in nmol/L of CAH girls at the time of CBCLa | 0.7 (3.3) |
aMean (standard deviation).
bMedian (range).
cFrequency (%).
CI: confidence interval.