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. 2014 Mar 17;13:106. doi: 10.1186/1475-2875-13-106

Table 1.

Histopathological changes and grading schemes used to evaluate liver tissues

Histopathologic changes Histopathologic grading
0 1 2 3
Fatty change
No fatty change
< 10%
10-50%
> 50%
Kupffer cells/HPF
< 20/HPF
20-35/HPF
36-50/HPF
> 50/HPF
Portal tract inflammation
< 5% of portal tract area
5-15% of portal tract area
16-30% of portal tract area
> 30% of portal tract area
Bile duct proliferation
No proliferation
Mild proliferation
Moderate proliferation
Severe proliferation
Sinusoid congestion
No congestion
Mild congestion
Moderate congestion
Severe congestion
Haemozoin deposition No deposition Mild deposition Moderate deposition Severe deposition

HPF = high power field (magnification 400x).