Table 3.
Univariate | Multivariable | |||||
---|---|---|---|---|---|---|
| ||||||
Mean (SD) | 95% CI | p-value | LS mean (SE) | 95% CI | p-value | |
Age at evaluation, years | - | - | 0.003 | - | - | 0.03 |
Age at diagnosis, years | ||||||
<5 | 0.56 (0.27) | 0.44-0.68 | 0.05 | 0.47 (0.08) | 0.31-0.63 | 0.76 |
5-20 | 0.40 (0.32) | 0.31-0.49 | 0.45 (0.05) | 0.34-0.55 | ||
Sex | ||||||
Male | 0.40(0.33) | 0.29-0.51 | 0.19 | 0.44 (0.06) | 0.31-0.57 | 0.60 |
Female | 0.50 (0.29) | 0.40-0.59 | 0.48 (0.06) | 0.35-0.61 | ||
Segmental radiation | ||||||
Posterior fossa/spine | ||||||
No | 0.42 (0.34) | 0.31-0.54 | 0.51 | 0.59 (0.09) | 0.41-0.76 | 0.08 |
Yes | 0.47 (0.28) | 0.38-0.57 | 0.34 (0.09) | 0.16-0.52 | ||
Temporal lobe | ||||||
No | 0.37(0.34) | 0.25-0.50 | 0.10 | 0.36 (0.09) | 0.18-0.55 | 0.09 |
Yes | 0.50 (0.29) | 0.41-0.58 | 0.56 (0.06) | 0.44-0.68 | ||
Frontal cortex | ||||||
No | 0.38(0.33) | 0.28-0.48 | 0.04 | 0.37(0.08) | 0.21-0.52 | 0.17 |
Yes | 0.53 (0.28) | 0.43-0.63 | 0.56 (0.09) | 0.37-0.74 | ||
Occipital/parietal lobe | ||||||
No | 0.42 (0.33) | 0.32-0.52 | 0.40 | 0.48 (0.09) | 0.29-0.66 | 0.81 |
Yes | 0.48 (0.29) | 0.38-0.59 | 0.44 (0.08) | 0.29-0.60 | ||
Shunt placement | ||||||
No | 0.41 (0.30) | 0.33-0.50 | 0.18 | 0.42 (0.06) | 0.30-0.55 | 0.32 |
Yes | 0.52(0.35) | 0.37-0.66 | 0.50 (0.07) | 0.37-0.63 | ||
Tumor type | ||||||
Astrocytic | 0.44 (0.33) | 0.33-0.55 | 0.15 | 0.45 (0.06) | 0.32-0.58 | 0.22 |
Medulloblastoma | 0.56(0.23) | 0.42-0.71 | 0.50(0.10) | 0.31-0.70 | ||
Ependymoma | 0.53 (0.30) | 0.31-0.76 | 0.59(0.12) | 0.35-0.83 | ||
Other | 0.31(0.32) | 0.14-0.49 | 0.30(0.10) | 0.11-0.49 | ||
Chemotherapy | ||||||
No | 0.41 (0.32) | 0.33-0.50 | 0.17 | 0.48 (0.07) | 0.35-0.61 | 0.77 |
Yes | 0.53 (0.29) | 0.40-0.65 | 0.45 (0.08) | 0.28-0.61 |