TABLE 1.
Sterol biosynthetic enzymes
| # | EC | KEGG | Enzyme Name |
| 1 | 2.3.1.9 | K00626 | Acetyl-CoA C-acetyltransferase |
| 2 | 2.3.3.10 | K01641 | Hydroxymethylglutaryl-CoA synthase |
| 3 | 1.1.1.34 | K00021 | Hydroxymethylglutaryl-CoA reductase (NADPH) |
| 4 | 1.1.1.88 | K00054 | Hydroxymethylglutaryl-CoA reductase |
| 5 | 2.7.1.36 | K00869 | Mevalonate (MEV) kinase |
| 6 | 2.7.4.2 | K00938 | Phospho-MEV kinase |
| 7 | 4.1.1.33 | K01597 | Diphospho-MEV decarboxylase |
| 8 | 2.2.1.7 | K01662 | 1-Deoxy-d-xylulose-5-phosphate synthase |
| 9 | 1.1.1.267 | K00099 | 1-Deoxy-d-xylulose-5-phosphate reductoisomerase |
| 10 | 2.7.7.60 | K00991 | 2-C-methyl-d-erythritol 4-phosphate cytidylyltransferase |
| 11 | 2.7.1.148 | K00919 | 4-Diphosphocytidyl-2-C-methyl-d-erythritol kinase |
| 12 | 4.6.1.12 | K01770 | 2-C-methyl-d-erythritol 2,4-cyclodiphosphate synthase |
| 13 | 1.17.7.1 | K03526 | (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase |
| 14 | 1.17.1.2 | K03527 | 4-Hydroxy-3-methylbut-2-enyl diphosphate reductase |
| 15 | 5.3.3.2 | K01823 | Isopentenyl-diphosphate delta-isomerase |
| 16 | 4.2.3.27 | K12742 | Isoprene synthase |
| 17 | 2.5.1.1 | K00787 | Geranyl diphosphate synthase |
| 18 | 2.5.1.68 | K12503 | Short-chain Z-isoprenyl diphosphate synthase |
| 19 | 2.5.1.86 | K14215 | Trans,polycis-decaprenyl diphosphate synthase |
| 20 | 2.5.1.10 | K00787 | Farnesyl diphosphate synthase |
| 21 | 2.5.1.21 | K00801 | Farnesyl-diphosphate farnesyltransferase |
| 22 | 1.14.13.132 | K00511 | Squalene monooxygenase |
| 23 | 5.4.99.7 | K01852 | Lanosterol synthase |
| 24 | 1.14.13.70 | K05917 | Cytochrome P450, family 51 (CYP51; sterol 14-demethylase) |
| 25 | 1.3.1.70 | K00222 | Delta14-sterol reductase |
| 26 | 1.14.13.72 | K07750 | Methylsterol monooxygenase |
| 27 | 1.1.1.170 | K07748 | Sterol-4α-carboxylate 3-dehydrogenase (decarboxylating) |
| 28 | 1.1.1.270 | K09827 | 3-Keto steroid reductase |
| 29 | 5.3.3.5 | K01824 | Cholestenol delta-isomerase |
| 30 | 1.3.1.72 | K09828 | Delta24-sterol reductase |
| 31 | 1.14.21.6 | K00227 | Lathosterol oxidase |
| 32 | 1.3.1.21 | K00213 | 7-Dehydrocholesterol reductase |
| 33 | 3.1.1.13 | K01052 | Lysosomal acid lipase/cholesteryl ester hydrolase |
| 34 | 2.3.1.26 | K00637 | Sterol O-acyltransferase |
| 35 | 1.14.13.13 | K07438 | Calcidiol 1-monooxygenase |
| 36 | 1.14.13.126 | K07436 | Vitamin D3 24-hydroxylase |
| 37 | 2.1.1.41 | K00559 | Sterol 24-C-methyltransferase |
| 38 | 5.-.-.- | K09829 | C-8 sterol isomerase |
| 39 | 1.3.1.71 | K00223 | Delta24[24 (1)]-sterol reductase |
| 40 | 5.4.99.8 | K01853 | Cycloartenol synthase |
| 41 | 2.1.1.143 | K08242 | 24-Methylenesterol C-methyltransferase |
| 42 | n.a. | K09832 | Cytochrome P450, family 710, subfamily A |
EC, Enzyme Commission number; KEGG, Kyoto Encyclopedia of Genes and Genomes identifier.