TABLE 7.
Median concentrations of all the examined bile acids obtained by the GC-MS method
| Control (n = 10) | Early (n = 17) | Advanced (n = 23) | ||
| μmol/g |
||||
| Totala | 4.93 | 3.63 | 1.18 | |
| Subtotalb | 4.77 | 3.53 | 0.85 | |
| Usual bile acids | ||||
| 1 | CA | 0.03 | 0.04 | 0.12 |
| 2 | CDCA | 0.01 | 0.03 | 0.16 |
| 3 | DCA | 3.25 | 1.27 | 0.01 |
| 4 | LCA | 0.31 | 0.17 | 0.02 |
| 5 | UDCA | 0.01 | 0.01 | 0.01 |
| 8 | isoDCA | 0.31 | 0.10 | 0.00 |
| 9 | isoLCA | 0.06 | 0.04 | 0.00 |
| 11 | HCA | 0.00 | 0.00 | 0.01 |
| 6, 7, 10, 12c | 0.00 | 0.00 | 0.00 | |
| Unsaturated bile acids | ||||
| 15–22c | 0.00 | 0.00 | 0.00 | |
| 24 | isoLCA-Δ5 | 0.00 | 0.00 | 0.01 |
| 23 | isoDCA-Δ5 | 0.00 | 0.00 | 0.01 |
| Hydroxylated bile acids | ||||
| 25–31c | 0.00 | 0.00 | 0.00 | |
| 32 | DCA-1β-ol | 0.01 | 0.00 | 0.00 |
| C27 bile acids | ||||
| 37, 38c | 0.00 | 0.00 | 0.00 | |
a
Sum of all the bile acid species examined by this method.
b
Total of CA, CDCA, DCA, LCA, isoDCA, isoLCA, UDCA, and HCA which are common bile acid species examined by three different methods.
c
Bile acids denoted by the compound numbers are given in the appendix.