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. Author manuscript; available in PMC: 2014 Apr 22.
Published in final edited form as: Chembiochem. 2012 Jul 17;13(12):1717–1724. doi: 10.1002/cbic.201200226

Figure 2.

Figure 2

Pattering SAMs using microfluidics. A) Microfluidic channels were adhered to a SAM substrate and used to locally conjugate a cell adhesion ligand (RGDSP) and a heparin-binding peptide (HEPpep). B) Schematic representation and fluorescent images of peptides patterned using microfluidics with control peptide (left) and HEPpep (right). C) hMSC number over time and bright-field photomicrographs at t= 72 h of hMSCs in regions presenting 2% RGDSP and 2% control peptide (left image), or 2% RGDSP and 2% HEPpep (right image). Scale bar=100 μm; an asterisk indicates significant difference compared to “control” at p<0.05. Adapted from ref. [6] with permission. Copyright: The Royal Society of Chemistry, 2011.