Table 1.
DNA sequence polymorphisms in each domain of PvMSP-3β among Korean isolates
| Fragment | Segregating sites (S) | Singleton variable sites | Parsimony informative sites | Total no. of mutations | K | H | Hd ± SD | π ± SD | dN-dS | Tajima’s D | Fu and Li’s D | Fu and Li’s F |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| N-terminal domain |
187 |
0 |
187 |
194 |
73.296 |
5 |
0.773 ± 0.028 |
0.07271 ± 0.00240 |
1.286 |
3.15439 (P < 0.01) |
2.53522 (P < 0.02) |
3.36192 (P < 0.02) |
| Insert A |
0 |
0 |
0 |
0 |
0 |
1 |
0 |
0 |
0 |
0 |
0 |
0 |
| C-terminal domain | 96 | 0 | 96 | 100 | 32.920 | 5 | 0.733 ± 0.028 | 0.03040 ± 0.00179 | 0.455 | 2.27420 (P < 0.05) | 2.39279 (P < 0.02) | 2.81226 (P < 0.02) |
K, average number of pairwise nucleotide differences; H, number of haplotypes; Hd, haplotype diversity; π, observed average pairwise nucleotide diversity; dN, rate of non-synonymous mutations; dS, rate of synonymous mutations.