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Expression of superoxide. O2- level detected by electron paramagnetic resonance (EPR) spin trapping spectroscopy in the lung, liver, and spleen tissues of the (A) C57BL/6 or (B)Tlr4-/- mice at 3 and 6 h after intraperitoneal injection of 500 μg LPS in the absence or presence of LY294002 injected 1 h prior. Bars represent mean ± SEM values from 6 experiments; *P < 0.05, **P < 0.01 vs. control.
