Skip to main content
. Author manuscript; available in PMC: 2015 May 1.
Published in final edited form as: J Hepatol. 2013 Dec 25;60(5):940–947. doi: 10.1016/j.jhep.2013.12.019

Table 3. Etiology-based comparison of microbiota: NASH.

Etiologies other than NASH (n=181) NASH cirrhosis (n=32)
Age 56.6±6.6 59.5±4.7*
BMI 28.6±5.8 35.3±4.7*
MELD score 12.7±5.9 12.0±7.3
Prior overt HE on treatment (%) 40% 34%
Endotoxin (EU/ml) 0.65±0.86 0.76±0.97
Microbiota (Phylum_Taxon)
Bacteroidetes Bacteroidaceae 19.3 42.7*
Bacteroidetes Porphyromonadaceae 1.4 3.9*
Firmicutes Veillonellaceae 1.9 0.0*
Cirrhosis Dysbiosis Ratio 0.80 0.63
*

p<0.05, we found a higher abundance of Porphyromonadaceae, Bacterioidaceae and lower Veillonellaceae in NASH patients who were also older and had a higher BMI than the non-NASH counterparts. No change in other bacteria from phylum Firmicutes was seen. Only bacterial taxa with an abundance >1% in either comparison are shown; rest were nonsignificant.