Table 3. Meta-analysis of associations between 5-HT2A, 5-HTT, LEPR polymorphisms and OSAS in the additive, dominant and recessive Models.
| SNP | Comparison | OR with 95%CI | Heterogeneity | Publication Bias | ||||
| χ2 | Q test | I2 | Tau2 | Begg's test | Egger's test | |||
| 5-HT2A 102 C/T | T vs C | 0.97(0.83–1.14) | 2.02 | 0.846 | 0.00% | 0 | 0.707 | 0.449 |
| TT vs CT | 1.07(0.81–1.40) | 1.98 | 0.852 | 0.00% | 0 | 0.133 | 0.087 | |
| TT vs CC | 0.93(0.67–1.29) | 2.07 | 0.839 | 0.00% | 0 | 1.000 | 0.699 | |
| CC vs CT | 1.13(0.84–1.50) | 5.63 | 0.344 | 11.20% | 0.017 | 0.452 | 0.213 | |
| TT+CT vs CC | 0.90(0.69–1.19) | 4.67 | 0.458 | 0.00% | 0 | 1.000 | 0.316 | |
| CC+CT vs TT | 0.98(0.76–1.26) | 1.06 | 0.957 | 0.00% | 0 | 0.707 | 0.263 | |
| 5-HT2A-1438 G/A | A vs G | 2.33(1.49–3.66) | 22.9 | 0 | 82.60% | 0.217 | 0.462 | 0.458 |
| AA vs GG | 4.22(2.38–7.49) | 8.49 | 0.075 | 52.90% | 0.222 | 1.000 | 0.989 | |
| GG vs AG | 0.66(0.31–1.40) | 15.2 | 0.004 | 73.60% | 0.524 | 0.806 | 0.296 | |
| AA vs AG | 2.78(2.03–3.81) | 2.33 | 0.675 | 0.00% | 0 | 0.806 | 0.543 | |
| AA+AG vs GG | 2.44(1.11–5.38) | 20.8 | 0 | 80.70% | 0.637 | 0.806 | 0.631 | |
| GG+AG vs AA | 0.30(0.23–0.40) | 3.53 | 0.473 | 0.00% | 0 | 0.806 | 0.747 | |
| 5-HTTLPR | S vs L | 0.80(0.67–0.95) | 0.07 | 0.995 | 0.00% | 0 | 1.000 | 0.435 |
| SS vs LL | 0.65(0.46–0.93) | 0.27 | 0.966 | 0.00% | 0 | 1.000 | 0.396 | |
| SS vs SL | 0.86(0.67–1.11) | 2.76 | 0.430 | 0.00% | 0 | 0.713 | 0.713 | |
| SL vs LL | 0.77 (0.54–1.11) | 3.60 | 0.308 | 16.70% | 0.031 | 0.734 | 0.547 | |
| SS+SL vs LL | 0.72(0.51–1.01) | 0.22 | 0.977 | 0.00% | 0 | 0.734 | 0.285 | |
| LL+SL vs SS | 1.25(0.99–1.59) | 0.98 | 0.805 | 0.00% | 0 | 0.734 | 0.557 | |
| 5-HTTVNTR | 10 vs 12 | 2.08(1.58–2.73) | 3.31 | 0.346 | 9.40% | 0.089 | 0.278 | |
| 10/10 vs 12/12 | 3.75(1.67–8.45) | 1.29 | 0.731 | 0.00% | 0 | 0.734 | 0.135 | |
| 10/10 vs 10/12 | 1.67(0.74–3.77) | 0.94 | 0.816 | 0.00% | 0 | 0.308 | 0.236 | |
| 10/12 vs 12/12 | 1.97(1.42–2.73) | 1.35 | 0.718 | 0.00% | 0 | 0.734 | 0.090 | |
| 10/10+10/12 vs 12/12 | 2.14(1.57–2.91) | 2.10 | 0.551 | 0.00% | 0 | 0.734 | 0.187 | |
| 10/10 vs 12/12+10/12 | 3.00(1.39–6.46) | 1.89 | 0.596 | 0.00% | 0 | 0.308 | 0.141 | |
| LEPR | G vs A | 0.78(0.58–1.05) | 3.73 | 0.155 | 46.40% | 0.009 | 1.000 | 0.791 |
| GG vs AA | 0.39(0.17–0.88) | 0.40 | 0.818 | 0.00% | 0 | 1.000 | 0.042 | |
| GG vs AG | 0.80(0.40–1.59) | 5.62 | 0.060 | 64.40% | 0.241 | 1.000 | 0.517 | |
| AA vs AG | 1.46(0.71–3.04) | 0.27 | 0.875 | 0.00% | 0 | 1.000 | 0.703 | |
| AA+AG vs GG | 1.32(0.65–2.67) | 6.11 | 0.047 | 67.30% | 0.260 | 1.000 | 0.652 | |
| GG+AG vs AA | 0.57(0.28–1.15) | 0.03 | 0.984 | 0.00% | 0 | 1.000 | 0.958 | |