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. 2014 Mar 11;7:137. doi: 10.1186/1756-0500-7-137

Table 1.

Clinical characteristics of 22 cases with human parvovirus B19 (HPV-B19) infection in adult patients with hereditary spherocytosis

Reference Age Gender Initial symptom Family history of HS Fever Splenomegaly Liver test abnormality Skin manifestation Gallstone Detection of HPV-B19
[4]
33
Female
Fever, abdominal pain, swelling of the hands, fatigue, headache, palpitations, dizziness
Yes
Yes
Yes
-
-
-
Antibody
[4]
28
Male
Lethargy, weakness, shivering, muscular pain, headache, palpitation, dizziness
Yes
-
Yes
-
-
-
Antibody
[5]
27
Male
Fever, night sweat, shivers, stiffness, headache, dry cough, dizziness
Yes
Yes
Yes
-
-
-
Antibody
[6]
27
Male
Fever, headache, pain, sweating, cough
Yes
Yes
Yes
-
-
-
Antibody
[6]
37
Female
Fever, headache, sore throat, pains, cough
-
Yes
Yes
-
-
-
Antibody
[7]
30
Female
-
-
-
-
-
-
-
Antibody
[8]
43
Female
Fever, headache, nausea, diarrhea
Yes
Yes
-
-
-
-
Antibody
[9]
34
Female
Fever, malaise, fatigue, palpitation, arthralgia, headache, dizziness
Yes
Yes
Yes
Yes
Yes
-
Antibody
[10]
34
Female
Fever, jaundice, anemia
Yes
Yes
Yes
-
-
-
Immunoelectrophoresis
[11]
18
Male
Vomiting, fever, lethargy
Yes
Yes
-
-
-
-
Antibody in situ hybridization
[12]
23
Female
Low back pain, arthralgia, fever, nausea, vomiting, diffuse abdominal pain
Yes
Yes
Yes
-
Yes
Yes
Antibody
[13]
36
Female
Fever, myalgia, malaise
-
Yes
Yes
-
-
-
Antibody, PCR
[14]
19
Male
Malaise, anorexia, night sweats
-
Yes
Yes
-
-
-
Antibody, PCR
[15]
27
Female
Arthralgia, pharyngitis, cough, nausea, vomiting, diarrhea
Yes
-
Yes
-
-
-
PCR
[16]
22
Female
Anemia, jaundice
-
-
Yes
-
-
-
Antibody
[17]
28
Male
Leg pain, fatigue
-
Yes
-
-
-
Yes
Antibody
[18]
19
Female
Fever, malaise, urinary frequency
Yes
Yes
Yes
-
-
Yes
Antibody, PCR
[18]
27
Female
Fever, malaise, splenomegaly
Yes
Yes
Yes
-
-
-
Antibody, PCR
[19]
19
Female
Nausea, vomiting, dyspnea, sever fatigue, anemia
Yes
Yes
-
Yes
-
Yes
Antibody, PCR
[20]
34
Female
Presyncope, fever, myalgia
-
Yes
Yes
-
-
-
Antibody, PCR
[21]
34
Female
Anemia, fever
-
Yes
Yes
Yes
-
Yes
Antibody
Present case 33 Female Fever, fatigue, nausea, anemia - Yes Yes Yes - Yes Antibody, PCR

A hyphen shows that there is no evidence or no description of each characteristic on the article.

HS, hereditary spherocytosis; HPV, human parvovirus; PCR, polymerase chain reaction.