Table 1. Values of sensitivity, specificity, positive and negative predictive values, positive and negative likelihood ratios for Adapted Scoring System (ASS), Modified Scoring System (MSS) and Scoring System with New Score (SSNS) according to the cut-off values (with the optimized cutoff value marked in “bold-face”), for HIV-infected adults and suspected smear-negative pulmonary TB, in Pernambuco, Brazil, 2007–2010.
| Number of points | Sensitivity | Specificity | Predictive value | Likelihood Ratio | |||
| Positive | Negative | Positive | Negative | ||||
| Adapted Scoring System (ASS) | |||||||
| ≥ −5 | 100% | 0% | 10.04% | – | 1.000 | – | |
| ≥0 | 96.09% | 10.5% | 10.70% | 96.01% | 1.074 | 0.370 | |
| ≥5 | 92.97% | 15.34% | 10.91% | 95.13% | 1.098 | 0.458 | |
| ≥10 | 92.97% | 19.35% | 11.40% | 96.10% | 1.153 | 0.363 | |
| ≥15 | 79.69% | 48.56% | 14.74% | 95.54% | 1.549 | 0.418 | |
| ≥20 | 60.94% | 64.69% | 16.15% | 93.68% | 1.726 | 0.604 | |
| ≥25 | 53.13% | 77.24% | 20.66% | 93.65% | 2.335 | 0.607 | |
| ≥30 | 48.44% | 82.82% | 23.93% | 93.50% | 2.820 | 0.622 | |
| ≥35 | 24.22% | 92.94% | 27.68% | 91.65% | 3.429 | 0.815 | |
| ≥40 | 11.72% | 95.82% | 23.83% | 90.67% | 2.800 | 0.921 | |
| ≥45 | 3.13% | 99.13% | 28.64% | 90.17% | 3.584 | 0.977 | |
| ≥50 | 0% | 100% | – | 89.96% | – | 1.000 | |
| Modified Scoring System (MSS) | |||||||
| ≥ −5 | 100% | 0% | 10.04% | – | 1.000 | – | |
| ≥0 | 96.09% | 9.85% | 10.63% | 95.76% | 1.066 | 0.396 | |
| ≥5 | 93.75% | 14.30% | 10.88% | 95.34% | 1.094 | 0.437 | |
| ≥10 | 93.75% | 17.96% | 11.31% | 96.26% | 1.143 | 0.348 | |
| ≥15 | 86.72% | 42.81% | 14.47% | 96.65% | 1.516 | 0.310 | |
| ≥20 | 76.56% | 55.54% | 16.12% | 95.50% | 1.722 | 0.422 | |
| ≥25 | 72.66% | 66.61% | 19.54% | 95.62% | 2.176 | 0.410 | |
| ≥30 | 66.41% | 75.68% | 23.35% | 95.28% | 2.730 | 0.444 | |
| ≥35 | 42.19% | 87.62% | 27.55% | 93.14% | 3.408 | 0.660 | |
| ≥40 | 31.25% | 91.98% | 30.30% | 92.30% | 3.896 | 0.747 | |
| ≥45 | 19.53% | 96.34% | 37.32% | 91.47% | 5.334 | 0.835 | |
| ≥50 | 10.16% | 98.95% | 51.92% | 90.80% | 9.708 | 0.908 | |
| ≥55 | 4.69% | 99.30% | 42.78% | 90.32% | 6.721 | 0.960 | |
| ≥60 | 3.13% | 99.83% | 67.26% | 90.22% | 17.922 | 0.970 | |
| >60 | 0% | 100% | – | 89.96% | – | 1.000 | |
| Scoring System with New Scores (SSNS) | |||||||
| ≥0 | 100% | 0% | 10.04% | – | 1.000 | – | |
| ≥5 | 100% | 0% | 10.04% | – | 1.000 | 0.000 | |
| ≥10 | 100% | 0.09% | 10.05% | 100% | 1.001 | 0.000 | |
| ≥15 | 99.22% | 17.35% | 11.81% | 99.50% | 1.200 | 0.045 | |
| ≥20 | 99.22% | 17.70% | 11.86% | 99.51% | 1.205 | 0.044 | |
| ≥25 | 97.66% | 32.35% | 13.87% | 99.20% | 1.443 | 0.072 | |
| ≥30 | 94.53% | 55.01% | 19.00% | 98.90% | 2.101 | 0.099 | |
| ≥35 | 87.50% | 71.40% | 25.45% | 98.08% | 3.060 | 0.175 | |
| ≥40 | 81.25% | 78.03% | 29.21% | 97.39% | 3.698 | 0.240 | |
| ≥45 | 67.97% | 85.44% | 34.25% | 95.98% | 4.668 | 0.375 | |
| ≥50 | 60.16% | 90.50% | 41.41% | 95.32% | 6.330 | 0.440 | |
| ≥55 | 50.78% | 95.03% | 53.27% | 94.54% | 10.219 | 0.518 | |
| ≥60 | 37.50% | 97.73% | 64.83% | 93.34% | 16.543 | 0.639 | |
| ≥65 | 23.44% | 98.95% | 71.36% | 92.05% | 22.402 | 0.774 | |
| ≥70 | 14.06% | 99.48% | 75.11% | 91.21% | 26.883 | 0.864 | |
| ≥75 | 5.47% | 99.91% | 87.15% | 90.45% | 62.729 | 0.946 | |
| ≥80 | 3.91% | 100% | 100% | 90.31% | 44.806 | 0.962 | |
| >80 | 0% | 100% | – | 89.96% | – | 1.000 | |
Sample size = 1276 individuals.