Table 3. Clinical characteristics of cases of acute infection of spotted fever group rickettsioses (SFGR) in Taiwan.
Case No. | Case 1 | Case 2 | Case 3 | Case 4 | Case 5 | Other case [33] a |
Clinical finaldiagnosis | UFD | UFD | Q fever | Scrub typhus | UFD | NA |
Identified SFGR | UndeterminedSFGR | Possible R. felis | Possible R. felis | Possible R. felis | UndeterminedSFGR | R. felis |
Age/Sex | 48/F | 50/M | 31/M | 67/M | 40/M | 27/F |
Underlying diseases | Nil | Alcoholism | Alcoholism, HCV | HBV, HCV, cirrhosis,diabetes mellitus | Nil | Nil |
Clinical symptomsand signs | Fever, chills, | Fever, chills,headache, skinrash, relativebradycardia | Fever, chills,headache, abdominalpain, myalgia,relative bradycardia | Fever, chills, cough,abdominal pain,myalgia, relativebradycardia | Fever, chills,headache | Fever, chills,headache, fatigue,acute polyneuropathy |
Resident in mountainarea/rural | Nil | Yes | Yes | Yes | Nil | Nil |
Recent travel in mountain/rural area | Yes | Nil | Nil | Nil | Nil | Nil |
Animal contact history | Dogs, chicken | Nil | Cattle | Nil | Nil | Nil |
Insects/arthropods bites | Nil | Nil | Nil | Nil | Nil | Nil |
Chest x-ray | Normal | Normal | Normal | Increased infiltrationover right lower lung | Normal | Normal |
Abdominal ultrasonography | Fatty liver | Fatty liver | Fatty liver,hepatosplenomegaly | Cirrhosis, splenomegaly,fatty liver, gallstonesand polyps | Fatty liver | NA |
Laboratory examination | Normal bloodcell count,elevatedliver enzymes(ALT/AST:122/188 U/L) | Thrombocytopenia(platelet count:113000/uL),elevated liverenzymes (ALT/AST:155/191 U/L) | Leukocytosis(WBC:14210/uL),elevated liverenzymes(ALT/AST:150/214 U/L) | Thrombocytopenia(platelet count:149000/uL), elevatedliver enzymes (ALT/AST:108/113 U/L) | Thrombocytopenia(69000/uL), elevatedliver enzymes(ALT/AST:208/46 U/L) | Normal blood cellcount, liver enzymes |
Antimicrobial treatment | Doxycycline | Moxifloxacin,doxycycline | Doxycycline | Doxycycline,levofloxacin | Doxycycline | Doxycycline |
Case 6 was reported by Tsai et al. [33].
Normal range of blood examinations: WBC (3600∼10600/uL), platelet count (150000∼400000 uL), ALT (0∼40 U/L), AST (0∼38 U/L).
UFD = Unknown febrile disease; HBV = Hepatitis B virus; HCV = Hepatitis C virus; ALT = Alanine transaminase; AST = Aspartate transaminase; WBC = White blood cell count; NA = Not available.