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. 2014 Apr 22;9(4):e95810. doi: 10.1371/journal.pone.0095810

Table 3. Clinical characteristics of cases of acute infection of spotted fever group rickettsioses (SFGR) in Taiwan.

Case No. Case 1 Case 2 Case 3 Case 4 Case 5 Other case [33] a
Clinical finaldiagnosis UFD UFD Q fever Scrub typhus UFD NA
Identified SFGR UndeterminedSFGR Possible R. felis Possible R. felis Possible R. felis UndeterminedSFGR R. felis
Age/Sex 48/F 50/M 31/M 67/M 40/M 27/F
Underlying diseases Nil Alcoholism Alcoholism, HCV HBV, HCV, cirrhosis,diabetes mellitus Nil Nil
Clinical symptomsand signs Fever, chills, Fever, chills,headache, skinrash, relativebradycardia Fever, chills,headache, abdominalpain, myalgia,relative bradycardia Fever, chills, cough,abdominal pain,myalgia, relativebradycardia Fever, chills,headache Fever, chills,headache, fatigue,acute polyneuropathy
Resident in mountainarea/rural Nil Yes Yes Yes Nil Nil
Recent travel in mountain/rural area Yes Nil Nil Nil Nil Nil
Animal contact history Dogs, chicken Nil Cattle Nil Nil Nil
Insects/arthropods bites Nil Nil Nil Nil Nil Nil
Chest x-ray Normal Normal Normal Increased infiltrationover right lower lung Normal Normal
Abdominal ultrasonography Fatty liver Fatty liver Fatty liver,hepatosplenomegaly Cirrhosis, splenomegaly,fatty liver, gallstonesand polyps Fatty liver NA
Laboratory examination Normal bloodcell count,elevatedliver enzymes(ALT/AST:122/188 U/L) Thrombocytopenia(platelet count:113000/uL),elevated liverenzymes (ALT/AST:155/191 U/L) Leukocytosis(WBC:14210/uL),elevated liverenzymes(ALT/AST:150/214 U/L) Thrombocytopenia(platelet count:149000/uL), elevatedliver enzymes (ALT/AST:108/113 U/L) Thrombocytopenia(69000/uL), elevatedliver enzymes(ALT/AST:208/46 U/L) Normal blood cellcount, liver enzymes
Antimicrobial treatment Doxycycline Moxifloxacin,doxycycline Doxycycline Doxycycline,levofloxacin Doxycycline Doxycycline
a

Case 6 was reported by Tsai et al. [33].

Normal range of blood examinations: WBC (3600∼10600/uL), platelet count (150000∼400000 uL), ALT (0∼40 U/L), AST (0∼38 U/L).

UFD = Unknown febrile disease; HBV = Hepatitis B virus; HCV = Hepatitis C virus; ALT = Alanine transaminase; AST = Aspartate transaminase; WBC = White blood cell count; NA = Not available.