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. 2014 Apr 22;9(4):e96091. doi: 10.1371/journal.pone.0096091

Figure 3. Effect of sesamin on OVA-induced recruitment of total inflammation cells and eosinophils in BALF.

Figure 3

The number of total inflammation cells (A), number of eosinophils (B), and percentage of eosinophils in total cells in BALF were dramatically upregulated in mice receiving OVA sensitization and challenge (n = 10) compared with mice receiving sham treatment (n = 6). In OVA-sensitized and challenged animals, both total inflammation cells and eosinophils were reduced in mice treated with 10 or 20 mg/kg sesamin (n = 6 and 7, respectively) but not with 1 mg/kg sesamin (n = 6), compared with mice treated with vehicles. Each bar represents the mean ± S.E.M. Statistical significance was defined as ### p<0.01 compared with the sham group; and * p<0.05, ** p<0.01, *** p<0.001 compared with the OVA+vehicle group.